Research

Metabolomics and Environmental Toxicology Laboratory

Research in Eze Group encompasses two major areas, namely, (i) metabolomics and exposomics, and (ii) environmental toxicology and bioremediation. With double doctorates in chemistry and biology, Dr. Eze leads the metabolomics and environmental toxicology laboratory, and employs the techniques of bioanalytical chemistry, environmental toxicology, metabolomics, exposomics, microbiology and genomics to address health and environmental problems. Some of our research have attracted the attention of the chemical and environmental science research community. For example, our publication in RSC Advances was selected and featured as one of the 2020 Hot Articles by the Royal Society of Chemistry. Similarly, following the publication of our novel bioremediation research in Nature Communications Earth and Environment, I was invited to write a Behind the Paper blog article for Nature Earth and Environment Community website. Key research themes are outlined below.

Metabolomics and exposomics

• Mass spectrometry-based metabolomics for disease diagnosis
• GC-MS and LC-MS bioassay method development for animal and plant metabolomics and exposomics studies
• Roles of secondary metabolites in plant disease progression
• Characterization of human exposure to environmental toxicants using targeted and untargeted exposomics

Environmental toxicology and bioremediation

• Chemical fate and transport in the environment
• Bioaccumulation and toxicity of organochlorine pesticides and polychlorinated biphenyls in aquatic organisms such as whales and dolphins
• Metabolism of exogenous chemicals such as food additives, hydrocarbons, halogenated organics, PFAS and microplastics
• Novel ecofriendly and cost-effective bioremediation methods for organic and inorganic pollutants
• Molecular biotechnology and microbial genomics