Publications

Johnson, B.S., Valentino, H., and Sobrado, P. (2024) Kinetic Characterization and Identification of Key Active Site Residues of the N-aspartate-L-hydroxylase, CreE. CheBioChem, 22:e202400350. doi: 10.1002/cbic.202400350.

Yu, H., Peng, C., Li, Y., Zhu, X., Huang, Y., Jiang, L., Chen, Z., Sobrado, P., Han, Q. (2024) Identification of a serine protease involved in Spinosad degradation in the yellow fever mosquito, Aedes aegypti. Pesticide Biochemistry and Physiology. Under review.

Zhu, X., Gong, X., Chen, J., Jiang, L., Liu, Y., Guo, Y., Sobrado, P., and Han, Q. (2024) Molecular and functional identification of tyrosine hydroxylase in the yellow fever mosquito, Aedes aegypti, under review

Johnson, S.B., Li, H., Valentino, H., and Sobrado, P. (2024) Mechanism of Nitrone Formation by a FlavinDependent Monooxygenase. Biochemistry. 63:1445-1459. doi: 10.1021/acs.biochem.3c00656

Johnson, S.B., Paasch, K., Shepard, S., and Sobrado, P. (2024) Kinetic Characterization of a Flavin-Dependent Monooxygenase from the Insect Food Crop Pest, Zonocerus variegatus. Arch. Biochem. Biophys. 754:109949. doi: 10.1016/j.abb.2024.109949

Pierdominici-Sottile, G., Palma, J., Ferrelli, L.M., and Sobrado, P., (2024) The dynamics of the flavin, NADPH, and active sire loops determine the mechanism of activation of class B flavin-dependent monooxygenases. Protein Sciences. 33(4):e4935. Doi: 10.1002/pro.4935.

Sobrado, P., and Neira, J.L., (2023) Paul F. Fitzpatrick: A life of editorial duties and elucidating the mechanism of enzyme action. Arch. Biochem. Biophys. 742:109635. doi: 10.1016/j.abb.2023.109635

Lyons, NS, Bogner, AN, Tanner, JJ, and Sobrado, P. (2022) Kinetic and Structural Characterization of a FlavinDependent Putrescine N-Hydroxylase from Acinetobacter baumannii. Biochemistry. 2022 Nov 15;61(22):26072620. doi: 10.1021/acs.biochem.2c00493.

Dye, KJ, Vogelaar, NJ, O’Hara, M, Sobrado, P, Santos W, Carlier PR, and Yang Z. (2022) Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds. Microbiol Spectr. Nov 15:e0387722. doi: 10.1128/spectrum.03877-22.

Valentino, H., and Sobrado, P. (2021) Characterization of nitro-forming enzyme involved in fosfazinomycin biosynthesis. Biochemistry. 60:2851-2864. doi: 10.1021/acs.biochem.1c00512

Valentino, H., Korasick, A.D., Bohac, T.J., Shapiro, J.A., Wencewicz, A.T., Tanner, J.J., and Sobrado, P. (2021) ACS Omega 6(28):18537-18547. doi: 10.1021/acsomega.1c03047

Dye, K.J., Vogelaar, N.J., Sobrado, P., Yang, Z. (2021) High-throughput screen for inhibitors of the Type IV Pilus Assembly ATPase PiB. 6: e00129-2. doi: 10.1128/mSphere.00129-21

Sobrado, P. (2021) Role of reduced flavin in dehalogenation reactions. Arch. Biochem. Biophys. 699:108765. doi: 10.1016/j.abb.2020.108696

Li, H., Forson, B., Eckshtain-Levi, M., Valentino, H., Martin Del Campo, J., Tanner, J.J., Sobrado, P. (2020) Biochemical Characterization of the Two-Component Flavin-Dependent Monooxygenase involved in Valanimycin Biosynthesis. Biochemistry, doi: 10.1021/acs.biochem.0c00679